A dual-wavelength spread spectrum-based spectroscopic system For time-domain near-infrared diffuse optical imaging

Konstantinos I. Papadimitriou; Jeremy C. Hebden; Simon R. Arridge; Samuel Powell

doi:10.1117/12.2507992

1 March 2019 A dual-wavelength spread spectrum-based spectroscopic system For time-domain near-infrared diffuse optical imaging

Konstantinos I. Papadimitriou, Jeremy C. Hebden, Simon R. Arridge, Samuel Powell

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Proceedings Volume 10874, Optical Tomography and Spectroscopy of Tissue XIII; 1087421 (2019) https://doi.org/10.1117/12.2507992
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

We advance our previous research on spread spectrum spectroscopy by adding spectroscopic functionality using a custom-made optical transceiver. The new transceiver module features a 680nm communications-grade verticalcavity surface-emitting laser (VCSEL) and matches the performance of commercial 10Gb/s optical transceivers, which allow for a sub-ns instrument response. The optical power of the VCSEL can be software-adjusted up to 2mW with ∼40μA driving current resolution. This module, combined with a commercially available Gigabit optical transceiver at 850nm, allows us to derive information about the optical properties of tissue-equivalent phantoms and the concentration of various haemodynamic parameters in in vivo measurements.

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Konstantinos I. Papadimitriou, Jeremy C. Hebden, Simon R. Arridge, and Samuel Powell "A dual-wavelength spread spectrum-based spectroscopic system For time-domain near-infrared diffuse optical imaging", Proc. SPIE 10874, Optical Tomography and Spectroscopy of Tissue XIII, 1087421 (1 March 2019); https://doi.org/10.1117/12.2507992

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KEYWORDS

Vertical cavity surface emitting lasers

Near infrared spectroscopy

Transceivers

Scattering

Absorption

Modulation

Hemodynamics

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