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9 March 2020 Effect of a mild, diffuse central retinal edema on light evoked outer retina optophysiology signals measured in vivo in mice with optical coherence tomography (Conference Presentation)
Robert J. Zawadzki, Pengfei Zhang, Ratheesh K. Meleppat, Edward N. Pugh Jr.
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Proceedings Volume 11218, Ophthalmic Technologies XXX; 112181A (2020) https://doi.org/10.1117/12.2550205
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
Over last few years Optical Coherence Tomography has allowed precise observations of the light-evoked opthophysiological response of the inner and outer retina. In mouse rods this manifests itself as outer segments elongation that is driven by phototransduction. Given the current model describing these observations as osmotically driven water movements we have decided to alter retinal water homeostasis to see if, and how the measured signals will be affected. Our observations of light-evoked retina responses during mild, diffuse central retinal edema confirmed that water plays a key role in this process.
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Robert J. Zawadzki, Pengfei Zhang, Ratheesh K. Meleppat, and Edward N. Pugh Jr. "Effect of a mild, diffuse central retinal edema on light evoked outer retina optophysiology signals measured in vivo in mice with optical coherence tomography (Conference Presentation)", Proc. SPIE 11218, Ophthalmic Technologies XXX, 112181A (9 March 2020); https://doi.org/10.1117/12.2550205
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KEYWORDS
Retina
Optical coherence tomography
In vivo imaging
Rods
Cones
Image segmentation
Light scattering
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