Analysis of individual lipoproteins and liposomes

David L. Robbins; John P. Nolan; James H. Jett; Richard A. Keller; Larry A. Sklar

doi:10.1117/12.274353

22 May 1997 Analysis of individual lipoproteins and liposomes

David L. Robbins, John P. Nolan, James H. Jett, Richard A. Keller, Larry A. Sklar

Proceedings Volume 2985, Ultrasensitive Biochemical Diagnostics II; (1997) https://doi.org/10.1117/12.274353
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

We describe the application of single molecule detection (SMD) technologies for the analysis of natural and synthetic transport systems. The need for advanced analytical procedures of these complex and important systems is presented with the specific enhancements afforded by SMD with flowing sample streams. In contrast to bulk measurements which yield only average values, measurement of individual species allows creation of population histograms form heterogeneous samples. The data are acquired in minutes and the analysis requires relatively small sample quantities. Preliminary data are presented from the analysis of low density lipoprotein, and multilamellar and unilamellar vesicles.

Citation Download Citation

David L. Robbins, John P. Nolan, James H. Jett, Richard A. Keller, and Larry A. Sklar "Analysis of individual lipoproteins and liposomes", Proc. SPIE 2985, Ultrasensitive Biochemical Diagnostics II, (22 May 1997); https://doi.org/10.1117/12.274353

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available