Panoramic epifluorescent visualization of cardiac action potential activity

Mark Anthony Bray; Marc Lin; John P. Wikswo Jr.

doi:10.1117/12.349420

26 May 1999 Panoramic epifluorescent visualization of cardiac action potential activity

Mark Anthony Bray, Marc Lin, John P. Wikswo Jr.

Proceedings Volume 3658, Medical Imaging 1999: Image Display; (1999) https://doi.org/10.1117/12.349420
Event: Medical Imaging '99, 1999, San Diego, CA, United States

Abstract

Optical imaging of transmembrane potentials in cardiac tissue is a rapidly growing technique in cardiac electrophysiology. Current studies typically use a monocular imaging setup, thus limiting investigation to a restricted region of tissue. However, studies of large-scale wavefront dynamics, especially those during fibrillation and defibrillation, require visualization of the entire epicardial surface. We have developed a panoramic cardiac visualization system using mirrors which performs two tasks: (1) reconstruction of the surface geometry of the heart, and 2) representation of the panoramic fluorescence information as a texture mapping onto the geometry that was previously created. This system permits measurements of epicardial electrodynamics over a geometrically realistic representation of the actual heart being studied.

Citation Download Citation

Mark Anthony Bray, Marc Lin, and John P. Wikswo Jr. "Panoramic epifluorescent visualization of cardiac action potential activity", Proc. SPIE 3658, Medical Imaging 1999: Image Display, (26 May 1999); https://doi.org/10.1117/12.349420

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