Paper
18 November 2013 Irradiation system for interstitial photodynamic therapy
L. Pacheco, S. Stolik, J. De la Rosa
Author Affiliations +
Proceedings Volume 8785, 8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications; 8785E9 (2013) https://doi.org/10.1117/12.2026479
Event: 8th Ibero American Optics Meeting/11th Latin American Meeting on Optics, Lasers, and Applications, 2013, Porto, Portugal
Abstract
Interstitial Photodynamic Therapy (IPDT) is a promising form of treatment of deep-seated and bulky malignant tumors, based on the lethal cell response to the photochemical reactions when drug is light activated in presence of oxygen. In order to accomplish an effective internal illumination, laser sources are preferably used because of two important reasons: the monochromatic light can be confined to the narrow absorption band of the drug and the laser beam is easily focused into optical fibers. In this work the development of a diode-laser-light-source is presented. The system is tuned by temperature to get a better match in the 5-ALA absorption band. This system also comprises a trifurcated fiber system to accomplish interstitial illumination.
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L. Pacheco, S. Stolik, and J. De la Rosa "Irradiation system for interstitial photodynamic therapy", Proc. SPIE 8785, 8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications, 8785E9 (18 November 2013); https://doi.org/10.1117/12.2026479
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KEYWORDS
Semiconductor lasers

Absorption

Laser sources

Photodynamic therapy

Light sources

Tissue optics

Ocean optics

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