Melanin microcavitation threshold in the near infrared

Morgan S. Schmidt; Paul K. Kennedy; Rebecca L. Vincelette; Kurt J. Schuster; Gary D. Noojin; Andrew W. Wharmby; Robert J. Thomas; Benjamin A. Rockwell

doi:10.1117/12.2036287

26 February 2014 Melanin microcavitation threshold in the near infrared

Morgan S. Schmidt, Paul K. Kennedy, Rebecca L. Vincelette, Kurt J. Schuster, Gary D. Noojin, Andrew W. Wharmby, Robert J. Thomas, Benjamin A. Rockwell

Author Affiliations +

Proceedings Volume 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications; 894109 (2014) https://doi.org/10.1117/12.2036287
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Thresholds for microcavitation of isolated bovine and porcine melanosomes were determined using single nanosecond (ns) laser pulses in the NIR (1000 – 1319 nm) wavelength regime. Average fluence thresholds for microcavitation increased non-linearly with increasing wavelength. Average fluence thresholds were also measured for 10-ns pulses at 532 nm, and found to be comparable to visible ns pulse values published in previous reports. Fluence thresholds were used to calculate melanosome absorption coefficients, which decreased with increasing wavelength. This trend was found to be comparable to the decrease in retinal pigmented epithelial (RPE) layer absorption coefficients reported over the same wavelength region. Estimated corneal total intraocular energy (TIE) values were determined and compared to the current and proposed maximum permissible exposure (MPE) safe exposure levels. Results from this study support the proposed changes to the MPE levels.

Citation Download Citation

Morgan S. Schmidt, Paul K. Kennedy, Rebecca L. Vincelette, Kurt J. Schuster, Gary D. Noojin, Andrew W. Wharmby, Robert J. Thomas, and Benjamin A. Rockwell "Melanin microcavitation threshold in the near infrared", Proc. SPIE 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications, 894109 (26 February 2014); https://doi.org/10.1117/12.2036287

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
8 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Absorption

Near infrared

Laser damage threshold

Temperature metrology

Beam splitters

Cavitation

Nd:YAG lasers

Show All Keywords

Keywords/Phrases

Search In:

Publication Years