7 March 2022Precise monitoring of skin cellular changes in vivo at the same micro-location over a long period of weeks using MPM based multimodality microscopy
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Summary: We developed a fully automated microregistration method that enables repeated in vivo skin microscopy imaging of the same tissue microlocation and specific cells over a long period of days and weeks with unprecedented precision. Applying this method in conjunction with in vivo multimodality multiphoton microscope, the behavior of human skin cells such as cell proliferation, melanin upward migration, blood flow dynamics, and epidermal thickness adaptation can be recorded over time, facilitating quantitative cellular dynamics analysis.
Yunxian (Giselle) Tian,Zhenguo Wu,Harvey Lui,Jianhua Zhao,Sunil Kalia, andHaishan Zeng
"Precise monitoring of skin cellular changes in vivo at the same micro-location over a long period of weeks using MPM based multimodality microscopy", Proc. SPIE PC11934, Photonics in Dermatology and Plastic Surgery 2022, PC1193406 (7 March 2022); https://doi.org/10.1117/12.2615707
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Yunxian (Giselle) Tian, Zhenguo Wu, Harvey Lui, Jianhua Zhao, Sunil Kalia, Haishan Zeng, "Precise monitoring of skin cellular changes in vivo at the same micro-location over a long period of weeks using MPM based multimodality microscopy," Proc. SPIE PC11934, Photonics in Dermatology and Plastic Surgery 2022, PC1193406 (7 March 2022); https://doi.org/10.1117/12.2615707