Urinary stones harvested from patients were under in-vitro investigation. Fluorescence measurements were performed either by taking images under blue light excitation light as well as measuring excitation-emission-matrixes. Ho:YAG-laser assisted fragmentation was performed in an aquarium set-up to derived fragmentation/dusting rates. FTIR-spectroscopy was used to identify the composition of the stone. Blue light fluorescence excitation resulted in fluorescence emission in different spectral regions spectroscopically proven by EEM-measurement. A correlation with FTIR-spectroscopy is performed. Fragmentation experiments resulted in a dependency to the applied energy/pulse and repetition rate. Using photonic techniques urinary stones could be categorized by their composition. The impact of fluorescence guidance during endoscopic laser lithotripsy will be discussed.
Ronald Sroka, Max Eisel, Thomas Pongratz, Keerthanan Ulaganathan, and Frank Strittmatter, "Investigations on the fluorescence of urinary stones: how to assist the MD (Conference Presentation)," Proc. SPIE 10038, Therapeutics and Diagnostics in Urology: Lasers, Robotics, Minimally Invasive, and Advanced Biomedical Devices, 1003804 (Presented at SPIE BiOS: January 28, 2017; Published: 19 April 2017); https://doi.org/10.1117/12.2254983.5369935439001.
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