Many biologically active molecules are chiral. Many drugs, which are currently in use, are supplied as an equimolar
mixture of enantiomers. Although they have the same chemical structure, i.e. are not distinguishable by conventional
Raman spectroscopy, most isomers of chiral drugs exhibit marked differences in biological activities such as
pharmacology, toxicology, pharmacokinetics, metabolism, etc. In this report we introduced a new spectroscopic tool to
extend nonlinear Raman spectroscopy to chiral substances.
Georgi I. Petrov and Vladislav V. Yakovlev, "Towards noninvasive drug distribution in tissues: coherent Raman microspectroscopy of chiral molecules," Proc. SPIE 10046, Visualizing and Quantifying Drug Distribution in Tissue, 1004604 (Presented at SPIE BiOS: January 28, 2017; Published: 21 February 2017); https://doi.org/10.1117/12.2252944.
Conference Presentations are recordings of oral presentations given at SPIE conferences and published as part of the conference proceedings. They include the speaker's narration along with a video recording of the presentation slides and animations. Many conference presentations also include full-text papers. Search and browse our growing collection of more than 14,000 conference presentations, including many plenary and keynote presentations.
Study of self-shadowing effect as a simple means to realize nanostructured thin films and layers with special attentions to birefringent obliquely deposited thin films and photo-luminescent porous silicon