We describe a scanning near-infrared fluorescence imager for through-skull non-invasive brain
imaging on live murine models. The captured photoluminescence feature through scattering media
was enhanced using a high sensitivity scientific CMOS sensor with the obtained spatial resolution of
15.63 μm, depth of field of 5 mm and an average local signal-to-noise ratio of 37.5 dB.
Hanh N. D. Le, Yung-Tian A. Gau, Arman Rahmim, Dean F. Wong, Dwight E. Bergles, and Jin U. Kang, "Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm," Proc. SPIE 10051, Neural Imaging and Sensing, 100510M (Presented at SPIE BiOS: January 31, 2017; Published: 8 February 2017); https://doi.org/10.1117/12.2250240.
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