This work is dedicated to development of the OCT system with angiography for everyday clinical use. Two major problems were solved during the development: compensation of specific tissue displacements, induced by contact scanning mode and physiological motion of patients (e.g. respiratory and cardiac motions) and on-line visualization of vessel net, to provide the feedback for system operator. The performance of the resulting OCT-based microangiography device with hand-held probe was evaluated by visualization of vessels nets of volunteers oral mucosa and skin on different locations (hands, face, abdomen etc.). Success-rate more than 90% was demonstrated during the experiments.
Alexander A. Moiseev, Grigory V. Gelikonov, Sergey Y. Ksenofontov, Valentin M. Gelikonov, Lev A. Matveev, Vladimir Y. Zaitsev, Alexander L. Matveev, Marina A. Sirotkina, Natalia D. Gladkova, and I. Alex Vitkin, "Real time OCT-based angiography device with hand-held probe (Conference Presentation)," Proc. SPIE 10053, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI, 1005315 (Presented at SPIE BiOS: January 31, 2017; Published: 19 April 2017); https://doi.org/10.1117/12.2254962.5371723152001.
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