A prototype mid-infrared spectral imaging system for rapid assessment of cells for cytological diagnosis is reported. Based on a fibre optic super-continuum source that has large spectral brightness and is coupled in to an acousto-optic tuneable filter that can rapidly scan over a set of wavelengths that are chosen to give a high level of selectivity for a specific skin disease. The system has the potential to collect an image cube of 100 wavelengths and 300k pixels in 2 seconds so that cells on living people could be analysed. The system has been evaluated with colon cells over 2700- 3100 cm-1.
Mark Farries, Jon Ward, Ian Lindsay, Jayakrupakar Nallala, and Peter Moselund, "Fast hyper-spectral imaging of cytological samples in the mid-infrared wavelength region," Proc. SPIE 10060, Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 100600Y (Presented at SPIE BiOS: February 01, 2017; Published: 17 February 2017); https://doi.org/10.1117/12.2250811.
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