Absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue, i.e. a sub-micrometer scale displacement happens within a couple of microseconds. In this study, we initially investigate the depth-resolved deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. Functional images can be reconstructed based on the detected deformation, which enables a new imaging modality called thermo-elastic deformation imaging (TDI). Our results show that the associated displacement is related to the optical absorption of the short laser pulses. The TDI images can provide tissue type information in addition to the conventional OCT images.
Tianshi Wang, Tom Pfeiffer, Min Wu, Wolfgang Wieser, Wolfgang Draxinger, Antonius F. W. van der Steen, Robert Huber, and Gijs van Soest, "Short pulse laser induced thermo-elastic deformation imaging," Proc. SPIE 10062, Optical Interactions with Tissue and Cells XXVIII, 100620C (Presented at SPIE BiOS: January 30, 2017; Published: 15 February 2017); https://doi.org/10.1117/12.2251502.
Conference Presentations are recordings of oral presentations given at SPIE conferences and published as part of the conference proceedings. They include the speaker's narration along with a video recording of the presentation slides and animations. Many conference presentations also include full-text papers. Search and browse our growing collection of more than 12,000 conference presentations, including many plenary and keynote presentations.