We present the optimization of an adaptive optics loop for retinal imaging. Generally, the wave-front is overdetermined compared to the number of corrector elements. The sampling of the sensor can be reduced while maintaining an efficient correction, leading to higher sensitivity, faster correction and larger dynamic range. An analytical model was developed to characterize the link between number of actuators, number of micro-lenses and correction performance. The optimized correction loop was introduced into a scanning laser ophthalmoscope. In vivo images of foveal photoreceptors were recorded and the obtained image quality is equivalent to the state of the art in retinal AO-imaging.
Marie Laslandes, Matthias Salas, Christoph K. Hitzenberger, and Michael Pircher, "Optimizing the sampling density of a wave-front sensor in adaptive optics systems: application to scanning laser ophthalmoscopy," Proc. SPIE 10073, Adaptive Optics and Wavefront Control for Biological Systems III, 1007318 (Presented at SPIE BiOS: January 30, 2017; Published: 21 February 2017); https://doi.org/10.1117/12.2250732.
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