High-quality core/shell CdSe/xCdS quantum dots (QDs) ranging from 3 to 20 nm in diameter were synthesized for use as Förster Resonance Energy Transfer (FRET) donors. gNQDs are carefully characterized for size, emission, absorption, QY, and brightness in both organic and aqueous solution. FRET has been verified in optimally designed systems that use short capping ligands and donor-acceptor pairs that have well-matched emission and absorption spectra. The interplay between shell thickness, donor-acceptor distance, and particle brightness is systematically analyzed to optimize our biosensor design.
Margaret Chern, Thuy Nguyen, and Allison Dennis, "‘Giant’ nanocrystal quantum dots (gNQDs) as FRET donors," Proc. SPIE 10078, Colloidal Nanoparticles for Biomedical Applications XII, 100780L (Presented at SPIE BiOS: January 29, 2017; Published: 22 February 2017); https://doi.org/10.1117/12.2261716.
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