A novel terahertz (THz) otoscope is designed and fabricated to help physicians to diagnose otitis media (OM) with both THz diagnostics and conventional optical diagnostics. The inclusion of indium tin oxide (ITO) glass in the THz otoscope allows physicians to diagnose OM with both THz and conventional optical diagnostics. To determine THz diagnostics for OM, we observed reflection signals from samples behind a thin dielectric film and found that the presence of water behind the membrane could be distinguished based on THz pulse shape. We verified the potential of this tool for diagnosing OM using mouse skin tissue and a human tympanic membrane samples prior to clinical application. The presence of water absorbed by the human membrane was easily distinguished based on differences in pulse shapes and peak-to-peak amplitudes of reflected THz pulses. The potential for early OM diagnosis using the THz otoscope was confirmed by alteration of THz pulse depending on water absorption level.
Tae-In Jeon, Young Bin Ji, Hyeon Sang Bark, Sam Kyu Noh, and Seung Jae Oh, "Development of terahertz otoscope for diagnosing otitis media (Conference Presentation)," Proc. SPIE 10081, Frontiers in Biological Detection: From Nanosensors to Systems IX, 100810P (Presented at SPIE BiOS: January 31, 2017; Published: 2 May 2017); https://doi.org/10.1117/12.2251700.5382458674001.
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