OCT is the gold standard for clinical diagnosis and treatment of many retinal diseases. Most clinical OCT systems are table top systems that can only image seated, compliant patients that can fixate. These systems are incapable of imaging several important patient populations including bedridden patients and infants. In this work we describe the use of a custom, light weight, handheld OCT probe based on a high speed swept source engine for imaging in the intensive care nursery. The probe uses custom optics, optomechanics, and a MEMS mirror to achieve a weight of only 211g. The portability and imaging speed of this probe facilitates repeat, volumetric, bedside imaging in a challenging imaging environment. To date we have imaged over 43 pre-term and full-term infants in the intensive care nursery, with some patients having up to 15 imaging sessions starting at 30 weeks post menstrual age. Volumetric OCT enables visualization of the complex 3D structures associated with retinal pathology that is unavailable to slower, B-scan based probes. Repeat imaging shows the development of both normal and diseased retinal structures. We believe that OCT imaging of these infants will reveal retinal abnormalities, enable further study of pediatric retinal diseases, and allow for better management and prediction of future visual outcomes.
Christian Viehland, Francesco LaRocca, Du Tran-Viet, Moseph Jackson-Atogi, Caelan Eckard, Brenton Keller, Cynthia A. Toth, and Joseph A. Izatt, "Imaging of pediatric pathology in the intensive care nursery using a custom handheld, ultra-compact, swept-source OCT probe (Conference Presentation)," Proc. SPIE 10474, Ophthalmic Technologies XXVIII, 1047416 (Presented at SPIE BiOS: January 28, 2018; Published: 14 March 2018); https://doi.org/10.1117/12.2290627.5751475968001.
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