Photodynamic therapy (PDT) has traditionally been used as a photochemical surgical tool. However, there are a plethora of cellular molecular events that occur following the process of photoactivation. These cellular molecular nuances following PDT initiation are being increasingly recognized and may be exploited to expand PDT from being applicable in the metastatic setting. Amongst these are microenvironmental factors, selection pressures and the increase or inhibition of cytokine release. Aspects of this broad hypothesis will be discussed in the presentation.
Tayyaba Hasan, "Broadening photodynamic therapy (PDT) applications to the metastatic setting? (Conference Presentation)," Proc. SPIE 10476, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVII, 1047603 (Presented at SPIE BiOS: January 27, 2018; Published: 14 March 2018); https://doi.org/10.1117/12.2297584.5751476565001.
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