Injuries to main vascular structures within the sub mucosa present a serious complication during surgery. There is no evidence-based treatment to prevent this type of injury, so detection is critical. Using a combination of absorption and fluorescence imaging we can detect blood vessel phantoms to a depth of 7 mm in intestinal sub-mucosa. Using an illumination source at 850, and reading the cross-polarized reflected signal also at 850 gives the absorption image. Simultaneous excitation of ICG at 785 nm creates a fluorescent response that is used for contrast enhancement.
Stewart Russell, Shirley Chan, Min Jing Zheng, Yury Budansky, and Robert R. Alfano, "Combination absorption and fluorescence for detection of vessels in intestinal sub-mucosa
(Conference Presentation)," Proc. SPIE 10489, Optical Biopsy XVI: Toward Real-Time Spectroscopic Imaging and Diagnosis, 104890V (Presented at SPIE BiOS: January 31, 2018; Published: 14 March 2018); https://doi.org/10.1117/12.2295377.5751465913001.
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