Aperture synthesis techniques such as Interferometric Synthetic Aperture Microscopy (ISAM) and digital refocusing allow to restore Optical Coherence Tomography (OCT) images in out-of-focus regions and obtain increased spatial resolution. Since these techniques are phase sensitive, they require object stability during OCT data acquisition. Since these techniques are manipulate volumetric data as well, application of the techniques to in vivo measurements require some motion correction procedure. In this work we will show that some of these correction procedures can obliterate not only local phase variations caused by the objects motion during the acquisition but local phase variations caused by defocusing, thus erasing information necessary for OCT image restoration. Ways of overcoming the problem are presented and discussed.
Alexander A. Moiseev, Grigory V. Gelikonov, Sergey Y. Ksenofontov, Pavel A. Shilyagin, and Valentine M. Gelikonov, "Motion and compression correction for in vivo OCT with synthesized aperture (Conference Presentation)," Proc. SPIE 10493, Dynamics and Fluctuations in Biomedical Photonics XV, 104930R (Presented at SPIE BiOS: January 29, 2018; Published: 15 March 2018); https://doi.org/10.1117/12.2292598.5752208512001.
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