Optical elastography emerged in the late 1990s as a way to non-invasively assess tissue biomechanical properties (i.e. optical palpation to sense tissue stiffness). Advances in optical engineering, such as optical coherence tomography, were essential to the growth of this field and provided the high-speed, high-resolution imaging required to quantify microscopic tissue deformation dynamics, which can be the basis for distinguishing normal and diseased tissue. This review will cover the development and evolution of optical elastography applications for ocular tissues and discuss the challenges to deploying this technology for clinical use.
Michael D. Twa, "Optical elastography and applications in ocular biomechanics (Conference Presentation)," Proc. SPIE 10496, Optical Elastography and Tissue Biomechanics V, 1049608 (Presented at SPIE BiOS: January 27, 2018; Published: 15 March 2018); https://doi.org/10.1117/12.2295222.5752219185001.
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