Thermo-mechanical effect of laser radiation is a basis of new method of normalization of intraocular pressure in glaucomatous eyes due to laser-assisted pore formation in eye sclera. Laser-induced creation of pores in sclera increases hydraulic permeability. Stability of laser-induced pore system is achieved via gas nano-bubbles arisen in the sclera under laser radiation as a result of temperature dependency of gas solubility. The stabilization of laser-induced gas and pore systems in the tissue is an important mechanism for a long lasting healing of glaucoma observed in clinical trials with one year follow-up.
Olga Baum, Sebastian Wachsmann-Hogiu, and Emil Sobol, "Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera
," Proc. SPIE 10496, Optical Elastography and Tissue Biomechanics V, 1049617 (Presented at SPIE BiOS: January 29, 2018; Published: 19 February 2018); https://doi.org/10.1117/12.2289885.
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