Cataracts is a common ocular pathology that increases the amount of intraocular scattering. It degrades the quality of vision by both blur and contrast reduction of the retinal images. In this work, we propose a non-invasive method, based on wavefront shaping (WS), to minimize cataract effects. For the experimental demonstration of the method, a liquid crystal on silicon (LCoS) spatial light modulator was used for both reproduction and reduction of the realistic cataracts effects. The LCoS area was separated in two halves conjugated with the eye’s pupil by a telescope with unitary magnification. Thus, while the phase maps that induced programmable amounts of intraocular scattering (related to cataract severity) were displayed in a one half of the LCoS, sequentially testing wavefronts were displayed in the second one. Results of the imaging improvements were visually evaluated by subjects with no known ocular pathology seeing through the instrument. The diffracted intensity of exit pupil is analyzed for the feedback of the implemented algorithms in search for the optimum wavefront. Numerical and experimental results of the imaging improvements are presented and discussed.
Pablo Artal, Augusto Arias, and Enrique Fernández, "Wavefront shaping to correct intraocular scattering," Proc. SPIE 10502, Adaptive Optics and Wavefront Control for Biological Systems IV, 105020Q (Presented at SPIE BiOS: January 28, 2018; Published: 23 February 2018); https://doi.org/10.1117/12.2290388.
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