Cadmium still represents a stigma for many research- and/or industrial applications. Some deleterious effects are attributed to Cadmium. In the present work, highly fluorescent Cadmium sulfide quantum dots are investigated by e.g. physical-chemical characterization. Most important however is their application as fluorescent probes for bio-imaging in living cells and tissues. This work presents their toxicological evaluation by means of in vivo studies. Bio-imaging experiments are performed without any pre-treatment. The toxicological studies performed, strongly indicate that the use of Cadmium based nanoparticles as fluorescent probes may be nonhazardous and not induce side effects for cells/tissues.
Patricia M. A. Farias, Lan Ma-Hock, Robert Landsiedel, and Bennard van Ravenzwaay, "Toxicological evaluation of Cd-based fluorescent nanoprobes by means of in vivo studies," Proc. SPIE 10508, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications X, 105080H (Presented at SPIE BiOS: January 30, 2018; Published: 20 February 2018); https://doi.org/10.1117/12.2289341.
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