In many applications such as fractional ablative laser treatments, pain control, and fat removal, it is crucial to determine the temperature distribution across different layers of the tissue. We present a hybrid model consisting of point-wise temperature measurements and mathematical modeling of the simultaneous conduction and phase-change heat transfer to determine the coupling between the surface temperature and the isotherm planes across the tissue. The high accuracy and reliability, low sensitivity to variations in tissue texture and structure, simple design and implementation, as well as non-invasive nature of the method employed make the new system a robust tool in monitoring the temperature distribution and controlling the cooling or heating rate. The new system significantly increases the efficacy, safety, and reliability of the tissue thermal management treatments and reduces the risk of damage to non-target tissues especially for aggressive treatments.
Sahar Juhani, Reza Monazami, and Dieter Manstien, "A non-invasive system to assess tissue temperature distribution (Conference Presentation)," Proc. SPIE 10510, Frontiers in Biological Detection: From Nanosensors to Systems X, 105100A (Presented at SPIE BiOS: January 29, 2018; Published: 15 March 2018); https://doi.org/10.1117/12.2291354.5752179965001.
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