Fluorescent nanodiamonds have proven useful as nontoxic probes for optical tracking of subcellular processes. Here, we demonstrate that a resonant magnetic field can be used to transfer spin polarization from intrinsic defects at nanodiamond surfaces into surrounding solution, enabling imaging of nanodiamond via MRI. In combination with fluorescence techniques, this new MRI modality promises to enable nanodiamond as a bioprobe for noninvasive imaging over subcellular to whole body lengthscales.
David Waddington, Mathieu Sarracanie, Huiliang Zhang, Najat Salameh, David Glenn, Ewa rej, Torsten Gaebel, Thomas Boele, Ronald Walsworth, David Reilly, and Matthew Rosen, "Nanodiamond-enhanced MRI: towards multimodality imaging of nanodiamond (Conference Presentation)," Proc. SPIE 10547, Advances in Photonics of Quantum Computing, Memory, and Communication XI, 1054707 (Presented at SPIE OPTO: January 30, 2018; Published: 14 March 2018); https://doi.org/10.1117/12.2299324.5751529300001.
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