Super-resolution ultrasound (SR-US) imaging can achieve a ten-fold resolution improvement compared with the traditional ultrasound technique, which is important for the medical diagnosis and treatment. However, challenges remain in SR-US imaging. In this paper, on one hand, a Gaussian fitting method, derived from optical localization microscopy, is used to improve the imaging spatial resolution of the SR-US. On the other hand, a plane wave technique is also used in US imaging for improving the imaging speed of the SR-US. To evaluate the performance of the proposed method, the numerical simulation was performed based on a phantom model. The experimental results indicate that by the use of a Gaussian fitting location method, combined with a plane wave transmission technique, we can accurately image the movement of microbubble in the phantom at a high frame rate, compared to the conventional B-model imaging. Hence, the technique makes it possible to achieve fast SR-US imaging.
Yuexia Shu, Minglei Lv, Ying Liu, Zhuangzhi Yan, Jiehui Jiang, and Xin Liu, "Super-resolution ultrasound imaging with Gaussian fitting method and plane wave transmission," Proc. SPIE 10578, Medical Imaging 2018: Biomedical Applications in Molecular, Structural, and Functional Imaging, 105780M (Presented at SPIE Medical Imaging: February 12, 2018; Published: 12 March 2018); https://doi.org/10.1117/12.2292956.
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