Mammography is not sufficiently effective for women with dense breast tissue – women who are at much higher risk for developing breast cancer. Consequently, many breast cancers go undetected at their treatable stage. Improved cancer detection and characterization for women with dense breast tissue is urgently needed. Our clinical study has shown that ultrasound tomography (UST) is an emerging technique that moves beyond B-mode imaging by its through transmission capabilities. Transmission ultrasound provides additional tissue parameters such as sound speed, attenuation, and through-transmission rendered tissue stiffness information. For women with dense breasts, these parameters can be used to assist in detecting malignant masses within glandular or fatty tissue and differentiating malignant and benign masses. This paper focuses on the use of waveform ultrasound sound speed imaging and tissue stiffness information generated using through-transmission data to characterize different breast tissues and breast masses. In-vivo examples will be given to assess its effectiveness.
Cuiping Li, Gursharan Sandhu, Michael Boone, Neb Duric, Peter Littrup, and Kenneth Bergman, "Breast tissue characterization with sound speed and tissue stiffness imaging (Conference Presentation)," Proc. SPIE 10580, Medical Imaging 2018: Ultrasonic Imaging and Tomography, 105800Y (Presented at SPIE Medical Imaging: February 15, 2018; Published: 14 March 2018); https://doi.org/10.1117/12.2294929.5751378478001.
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