X-ray phase differences are a thousand times greater than attenuation differences, but phase imaging has found limited clinical use due to requirements on x-ray coherence which may not be easily translated to clinical practice. Instead, this work employs a conventional source to create structured illumination with a simple wire mesh. The system simultaneously collects phase, attenuation, and scatter information. X-ray coherent scatter allows differentiation between tissue types with potentially much higher contrast than conventional radiography. Coherent-scatter images are collected with simple 1D slot-scanning and an angular shield to select signatures of interest from a relatively large region.

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Rohaan Khan, Brenda Adhiambo, Sean Starr-Baier, Laila Hassan, Weiyuan Sun, Danhong Li, C. A. MacDonald, and Jonathan C. Petruccelli, "Low dose imaging with simultaneous scatter, attenuation and mesh-based phase contrast," Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109481T (Presented at SPIE Medical Imaging: February 20, 2019; Published: 1 March 2019); https://doi.org/10.1117/12.2512748.