From Event: SPIE Optical Engineering + Applications, 2019
Severe sepsis accounts for a third of patient deaths in the intensive care units worldwide therefore early sepsis detection and therapy onset is crucial for reduction of patient mortality and expenditures. In the present study the device prototype for sepsis bedside diagnostics is proposed, by combining hyperspectral and thermal imaging. The diagnostic principle is based on evaluation of skin oxygenation and micro perfusion inhomogeneity. Preliminary results confirm early heterogeneity detection of skin oxygenation (hemoglobin saturation with oxygen) and temperature caused by oxygen utilization and blood perfusion impairments. The present findings indicate on high sensitivity of developed prototype compared to routine subjective visual assessment of patient’s skin by clinicians.
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M. Lācis, S. Kazune, Z. Marcinkevics, U. Rubins, and A. Grabovskis, "Hybrid optical prototype for sepsis bedside diagnostics," Proc. SPIE 11105, Novel Optical Systems, Methods, and Applications XXII, 111050P (Presented at SPIE Optical Engineering + Applications: August 14, 2019; Published: 9 September 2019); https://doi.org/10.1117/12.2529230.