From Event: SPIE LASE, 2023
Bacillus cereus (Bc) group are spore-forming bacteria that include human pathogenic strains, such as Bacillus cereus and Bacillus anthracis. Detection of Bc group spores using selective media is a laborious process that is largely dependent on the laboratory environment. We have examined the application of so-called digital photocorrosion (DIP) GaAs/AlGaAs biosensor for detection of Bacillus thuringiensis (Bt) spores. With the aptamer-based biosensing architecture, we have successfully demonstrated detection of Bt spores in the range between 103 - 105 spores/mL. The ease of operating DIP biosensors, and the potential for sensitive detection in field settings hold the promise of attractive applications of these innovative devices for monitoring the presence of Bc group spores.
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Ishika Ishika, Walid M. Hassen, Houman Moteshareie, Azam F. Tayabali, and Jan J. Dubowski, "Detection of Bacillus group spores in an aqueous environment using an aptamer based digital photocorrosion biosensor," Proc. SPIE 12410, Nanoscale and Quantum Materials: From Synthesis and Laser Processing to Applications 2023, 1241003 (Presented at SPIE LASE: January 28, 2023; Published: 15 March 2023); https://doi.org/10.1117/12.2662421.
