The single-atom thickness of monolayer graphene makes it an ideal candidate for DNA sequencing as it can scan molecules passing through a nanopore at high resolution. Additionally, unlike most insulating membranes, graphene is electrically active, and this property can be exploited to control and electronically sense biomolecules. We show that the shape of the edge as well as the shape and position of the nanopore can strongly affect the electronic conductance through a lateral constriction in a graphene nanoribbon as well as its sensitivity to external charges. In this context the geometry of the graphene membrane can be tuned to detect the rotational and positional conformation of a charge distribution inside the nanopore. We show that a quantum point contact (QPC) geometry is suitable for the electrically-active graphene layer and propose a viable design for a graphene-based DNA sequencing device.
Jean-Pierre Leburton, "Genomics with graphene nanotechnology (Presentation Recording)," Proc. SPIE 9552, Carbon Nanotubes, Graphene, and Emerging 2D Materials for Electronic and Photonic Devices VIII, 955208 (Presented at SPIE Nanoscience + Engineering: August 09, 2015; Published: 5 October 2015); https://doi.org/10.1117/12.2186646.4519371084001.
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