Biological applications can benefit from nanoscale texturing of materials for biomedical functions. Texturing of
biomaterials can increase the available surface area so that they can be coated with larger doses of therapeutic agents.
We demonstrate nano-texturing of poly (L-lactic acid) (PLLA) – a prototypical material commonly used for drug-eluting
coronary stents and as a template for cell growth. A master pattern consisting of a periodic array was transferred to a
PDMS mold. Drop-casting PLLA achieves the best transfer of patterns, with nanoarrays of holes with pitch ~700 nm.
Nanoimprinting the PLLA films results in shallower and less resolved features.
Akshit Peer, Rabin Dhakal, Rana Biswas, and Jaeyoun Kim, "Nanoscale patterning of poly (L-lactic acid) films with nanoimprinting methods," Proc. SPIE 9556, Nanoengineering: Fabrication, Properties, Optics, and Devices XII, 95560X (Presented at SPIE Nanoscience + Engineering: August 12, 2015; Published: 20 August 2015); https://doi.org/10.1117/12.2188888.
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