Photodynamic therapy (PDT) has been theoretically investigated using a Monte Carlo radiation transfer (MCRT)
model. By including complex three dimensional (3D) tumour models a more appropriate representation of the
treatment was achieved. The 3D clustered tumour model was compared to a smooth model, resulting in a
significantly deeper penetration associated with the clustered model. The results from the work presented here
indicates that light might penetrate deeper than suggested by 2D or simple layered models.
C. Louis Campbell, Kenneth Wood, C. Tom A. Brown, and Harry Moseley, "New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling," Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96890Q (Presented at SPIE BiOS: February 14, 2016; Published: 29 February 2016); https://doi.org/10.1117/12.2212240.
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