Cherenkov imaging during radiotherapy is a method by which an optical analog for the high-energy radiation beam can
be observed directly on the surface of the patient. While simple geometries and volumes demonstrate a strong
correlation between Cherenkov emission intensity and surface dose, in vivo data collected from 14 whole-breast patients
has not exhibited the same correlation. The purpose of this anthropomorphic phantom study was to investigate a new
method for improving the in vivo correlation based on a pixel-by-pixel correction from a reference reflectance image.
The pixel intensities in Cherenkov images of a phantom were correlated with the surface dose measured from
thermoluminescent dosimeters (TLDs) placed on the phantom’s surface. Because the phantom had homogeneous optical
properties, results show a no appreciable change in correlation between Cherenkov intensity and surface dose when
using the correction method on images of an anthropomorphic solid silicone phantom, nor a change in the dose fall-off at
the edges of the phantom. The method may improve correlation with in vivo data.
Jacqueline M. Andreozzi, Rongxiao Zhang, Adam K. Glaser, David J. Gladstone, Lesley A. Jarvis, and Brian W. Pogue, "Using a reflectance-based correction on Cherenkov images to strengthen correlation with radiation surface dose in an anthropomorphic breast phantom," Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 968941 (Presented at SPIE BiOS: February 14, 2016; Published: 29 February 2016); https://doi.org/10.1117/12.2212648.
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