Photoacoustic (PA) technique involving both ultrasound and light has been explored for potential application in the assessment of bone health. The optical and ultrasound penetration in bone have been studied. The feasibility of conducting 3D PA imaging of bone, and performing quantitative evaluation of bone microstructures by using photoacoustic spectrum analysis (PASA) has also been investigated. The findings from the experiments demonstrate that PA measurement could offer information of bone mineral density and bone microstructure, both relevant to bone health.
Ting Feng, Ken Kozloff, Meng Cao, Qian Cheng, Jie Yuan, and Xueding Wang, "Study of photoacoustic measurement of bone health based on clinically relevant models," Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96894F (Presented at SPIE BiOS: February 13, 2016; Published: 29 February 2016); https://doi.org/10.1117/12.2211516.
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