Laser radiation entering the eye has the potential of damaging the retina. As an inflammatory response, the proteins can rush to the lesion site created by laser exposure. We explore the hypothesis if these proteins can be detected non-invasively. In this preliminary study, we developed a new brief-case size dynamic light scattering instrument to detect these proteins in-vivo in the rabbit vitreous. The results were validated with bio-chemical analysis.
Rafat R. Ansari, Melissa Naiman, Rachida Bouhenni, Jeffery Dunmire, Ying Liu, Qundeel Rafiq, Deepak Edward, and David Gothard, "Non-invasive detection of laser-induced retinal injury through the vitreous using dynamic light scattering
(Conference Presentation)," Proc. SPIE 9693, Ophthalmic Technologies XXVI, 969317 (Presented at SPIE BiOS: February 14, 2016; Published: 26 April 2016); https://doi.org/10.1117/12.2214980.4848636523001.
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Monte Carlo based light propagation models to improve efficacy of biophotonics based therapeutics of hollow organs and solid tumours including photodynamic therapy and photobiomodulation (Conference Presentation)