Morbidity and complexity involved in lymph node staging via surgical resection and biopsy calls for staging techniques that are less invasive. While visible blue dyes are commonly used in locating sentinel lymph nodes, since they follow tumor-draining lymphatic vessels, they do not provide a metric to evaluate presence of cancer. An area of active research is to use fluorescent dyes to assess tumor burden of sentinel and secondary lymph nodes. The goal of this work was to successfully perform fluorescence imaging of IRDye®680RD in the lymphatics, in a repeatable manner.
Alisha V. DSouza, Kayla A. Marra, Jason R. Gunn, Kimberley S. Samkoe, Kenneth M. Tichauer, and Brian W. Pogue, "Methods for effective fluorophore injection and imaging of lymphatics in small animals," Proc. SPIE 9696, Molecular-Guided Surgery: Molecules, Devices, and Applications II, 96960W (Presented at SPIE BiOS: February 14, 2016; Published: 4 March 2016); https://doi.org/10.1117/12.2213675.
Conference Presentations are recordings of oral presentations given at SPIE conferences and published as part of the proceedings. They include the speaker's narration with video of the slides and animations. Most include full-text papers. Interactive, searchable transcripts and closed captioning are now available for most presentations.
Search our growing collection of more than 26,000 conference presentations, including many plenaries and keynotes.