In this study, we have developed an acoustic radiation force orthogonal excitation optical coherence elastography
(ARFOE-OCE) method for the visualization of the shear wave and the calculation of the shear modulus based on the OCT
Doppler variance method. The vibration perpendicular to the OCT detection direction is induced by the remote acoustic
radiation force (ARF) and the shear wave propagating along the OCT beam is visualized by the OCT M-scan. The
homogeneous agar phantom and two-layer agar phantom are measured using the ARFOE-OCE system. The results show
that the ARFOE-OCE system has the ability to measure the shear modulus beyond the OCT imaging depth. The OCT
Doppler variance method, instead of the OCT Doppler phase method, is used for vibration detection without the need of
high phase stability and phase wrapping correction. An M-scan instead of the B-scan for the visualization of the shear
wave also simplifies the data processing.
Jiang Zhu, Yusi Miao, Yueqiao Qu, Teng Ma, Rui Li, Yongzhao Du, Shenghai Huang, K. Kirk Shung, Qifa Zhou, and Zhongping Chen, "Imaging shear wave propagation for elastic measurement using OCT Doppler variance method," Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 96971P (Presented at SPIE BiOS: February 17, 2016; Published: 8 March 2016); https://doi.org/10.1117/12.2214266.
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