Multiple reference optical coherence tomography (MR-OCT) applies a unique low-cost solution to enhance the scanning depth of standard time domain OCT by inserting an partial mirror into the reference arm of the interferometric system. This novel approach achieves multiple reflections for different layers and depths of an sample with minimal effort of engineering and provides an excellent platform for low-cost OCT systems based on well understood production methods for micro-mechanical systems such as CD/DVD pick-up systems. The direct integration of a superluminescent light-emitting diode (SLED) is a preferable solution to reduce the form- factor of an MR-OCT system. Such direct integration exposes the light source to environmental conditions that can increase fluctuations in heat dissipation and vibrations and affect the noise characteristics of the output spectrum. This work describes the impact of relative intensity noise (RIN) on the quality of the interference signal of MR-OCT related to a variety of environmental conditions, such as temperature.
Kai Neuhaus, Hrebesh Subhash, Sergey Alexandrov, Roshan Dsouza, Josh Hogan, Carol Wilson, Martin Leahy, Svetlana Slepneva, and Guillaume Huyet, "The impact of relative intensity noise on the signal in multiple reference optical coherence tomography," Proc. SPIE 9699, Optics and Biophotonics in Low-Resource Settings II, 96990P (Presented at SPIE BiOS: February 14, 2016; Published: 8 March 2016); https://doi.org/10.1117/12.2211404.
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