The extension of supercontinuum (SC) sources into the mid-infrared, via the use of uoride and chalcogenide optical fibers, potentially offers the high radiance of a laser combined with spectral coverage far exceeding that of typical tunable lasers and comparable to traditional black-body emitters. Together with advances in mid-IR imaging detectors and novel tunable filter designs, such supercontinua hold considerable potential as sources of illumination for spectrally-resolved microscopy targeting applications such as rapid histological screening. The ability to rapidly and arbitrarily select particular wavelengths of interest from a broad emission spectrum, covering a wide range of biologically relevant targets, lends itself to image acquisition only at key relevant wavelengths leading to more manageable datasets. However, in addition to offering new imaging modalities, SC sources also present a range of challenges to successful integration with typical spectral microscopy instrumentation, including appropriate utilisation of their high spatial coherence. In this paper the application of SC sources to spectrally-resolved microscopy in the mid-IR is discussed and systems-integration considerations specific to these sources highlighted. Preliminary results in the 3-5μm region, obtained within the European FP7 project MINERVA, are also presented here.
I. D. Lindsay, S. Valle, J. Ward, G. Stevens, M. Farries, L. Huot, C. Brooks, P. M. Moselund, R. M. Vinella, M. Abdalla, D. de Gaspari, R. M. von Wurtemberg, S. Smuk, H. Martijn, J. Nallala, N. Stone, C. Barta, R. Hasal, U. Moller, O. Bang, S. Sujecki, and A. Seddon, "Towards supercontinuum-driven hyperspectral microscopy in the mid-infrared," Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 970304 (Presented at SPIE BiOS: February 15, 2016; Published: 7 March 2016); https://doi.org/10.1117/12.2210836.
Conference Presentations are recordings of oral presentations given at SPIE conferences and published as part of the proceedings. They include the speaker's narration with video of the slides and animations. Most include full-text papers. Interactive, searchable transcripts and closed captioning are now available for most presentations.
Search our growing collection of more than 29,500 conference presentations, including many plenaries and keynotes.