Imaging technologies working in the spatial frequency domain are becoming increasingly popular for generating wide-field optical property maps, enabling further analysis of tissue parameters such as absorption or scattering. While acquisition methods have witnessed a very rapid growth and are now performing in real-time, processing methods are yet slow preventing information to be acquired and displayed in real-time. In this work, we present solutions for rapid inverse problem solving for optical properties by use of advanced look-up tables. In particular, we present methods and results from a dense, linearized look-up table and an analytical representation that currently run 100 times faster than the standard method and within 10% in both absorption and scattering. With the resulting computation time in the tens of milliseconds range, the proposed techniques enable video-rate feedback of real-time techniques such as snapshot of optical properties (SSOP) imaging, making full video-rate guidance in the clinic possible.
Joseph P. Angelo, Irving J. Bigio, and Sylvain Gioux, "Rapid spatial frequency domain inverse problem solutions using look-up tables for real-time processing
(Conference Presentation)," Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 97030U (Presented at SPIE BiOS: February 16, 2016; Published: 26 April 2016); https://doi.org/10.1117/12.2213255.4848650677001.
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