Polarization gating is a popular and widely used technique in biomedical optics to sense superficial tissues (collinear detection), deeper volumes (cross-linear detection), and also selectively probe deeper volumes (using elliptically polarized light). As opposed to the conventional linearly polarized illumination, we propose a new protocol of polarization gating that combines co-elliptical and counter-elliptical measurements to selectively enhance contrast of the images. In vivo experiments were performed on skin abnormalities of volunteers (to selectively probe and access subsurface information).
Susmita Sridhar and Anabela Da Silva, "Protocol using elliptically polarized light for enhanced contrast in polarization gating imaging of biological tissues," Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 970319 (Presented at SPIE BiOS: February 17, 2016; Published: 7 March 2016); https://doi.org/10.1117/12.2208760.
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