Lab-on-a-chip devices are often applied to point-of-care diagnostic solutions as they are low-cost, compact, disposable, and require only small sample volumes. For such devices, various reagents are required for sample preparation and analysis and, for an integrated solution to be realized, on-chip reagent storage and automated introduction are required. This work describes the implementation and characterization of effective liquid reagent storage and release mechanisms utilizing blister pouches applied to various point-of-care diagnostic device applications. The manufacturing aspects as well as performance parameters are evaluated.
Suzanne Smith, Rene Sewart, Kevin Land, Pieter Roux, Claudia Gärtner, and Holger Becker, "Blister pouches for effective reagent storage and release for low cost point-of-care diagnostic applications," Proc. SPIE 9705, Microfluidics, BioMEMS, and Medical Microsystems XIV, 97050F (Presented at SPIE BiOS: February 14, 2016; Published: 18 March 2016); https://doi.org/10.1117/12.2217963.
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