We propose a novel multispectral reconstruction-classification method for simultaneously recovering absorption and scattering coefficients from images of absorbed optical energy. In contrast with pre-existing chromophore reconstruction methods, this approach does not require prior knowledge of the characteristic spectra of the absorbers, which is not always available. Numerical experiments performed on anatomically realistic 3D phantoms show that this approach allows for improved recovery of both the optical absorption and scattering with respect to reconstruction-only methods, and accurate classification of chromophores of clinical interest.
Emma Malone, Ben Cox, and Simon Arridge, "Multispectral reconstruction methods for quantitative photoacoustic tomography," Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 970827 (Presented at SPIE BiOS: February 17, 2016; Published: 15 March 2016); https://doi.org/10.1117/12.2212440.
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