A novel method, an in situ autologous whole-cell cancer vaccine (inCVAX), is being developed by Immunophotonics, Inc., for the treatment of metastatic cancers. inCVAX combines phototherapy and immunotherapy to potentially induce a systemic anti-tumor immune response in the hosts. Immunophotonics and its academic partners have spent years conducting nonclinical research, developing CMC techniques and conducting clinical research. In 2015 the company initiated a late-stage (II/III) clinical trial in South America for advanced breast cancer patients. The process of developing the inCVAX approach from a laboratory setting into clinical trials requires significant efforts from a group of dedicated engineers, scientists, and physicians. The growth of the company and its business advances demonstrated the determination of a group of visionary investors, entrepreneurs, and business leaders. This talk will chronicle the milestones of the scientific achievement, medical progress, and business development of Immunophotonics.
Tomas Hode, Luciano Alleruzzo, Joseph Raker, Samuel Siu Kit Lam, Robert E. Nordquist, Wei R. Chen, and Aamr M. Hasanjee, "Development of InCVAX as a novel in situ autologous vaccine for metastatic cancers (Conference Presentation)," Proc. SPIE 9709, Biophotonics and Immune Responses XI, 97090I (Presented at SPIE BiOS: February 16, 2016; Published: 27 April 2016); https://doi.org/10.1117/12.2216110.4828165411001.
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