The ability to non-invasively focus light through scattering media has significant applications in many fields ranging from nanotechnology to deep tissue sensing. Until recently, the multiple light scattering events that occur in complex media such as biological tissue have inhibited the focusing ability and penetration depth of optical tools. Through the use of optical wavefront shaping, the spatial distortions due to these scattering events can be corrected, and the incident light can be focused through the scattering medium. Here, we demonstrate that wavefront shaping can be used to non-invasively enhance the Raman signal of a material through a scattering medium. Raman signal enhancement was achieved using backscattered light and a continuous sequential algorithm. Our results show the potential of wavefront shaping as an important addition to non-invasive detection techniques.
Jonathan V. Thompson, Graham A. Throckmorton, Brett H. Hokr, and Vladislav V. Yakovlev, "Optical wavefront shaping for the enhancement of Raman signal in scattering media," Proc. SPIE 9717, Adaptive Optics and Wavefront Control for Biological Systems II, 97170M (Presented at SPIE BiOS: February 14, 2016; Published: 15 March 2016); https://doi.org/10.1117/12.2213625.
Conference Presentations are recordings of oral presentations given at SPIE conferences and published as part of the proceedings. They include the speaker's narration with video of the slides and animations. Most include full-text papers. Interactive, searchable transcripts and closed captioning are now available for most presentations.
Search our growing collection of more than 26,000 conference presentations, including many plenaries and keynotes.