External beam radiotherapy utilizes high energy radiation to target cancer with dynamic, patient-specific treatment plans. The otherwise invisible radiation beam can be observed via the optical Cherenkov photons emitted from interaction between the high energy beam and tissue. Using a specialized camera-system, the Cherenkov emission can thus be used to track the radiation beam on the surface of the patient in real-time, even for complex cases such as volumetric modulated arc therapy (VMAT). Two patients undergoing VMAT of the head and neck were imaged and analyzed, and the viability of the system to provide clinical feedback was established.
Jacqueline M. Andreozzi, Rongxiao Zhang, Adam K Glaser, David J. Gladstone, Lesley A. Jarvis, and Brian W. Pogue, "Cherenkov imaging during volumetric modulated arc therapy for real-time radiation beam tracking and treatment response monitoring," Proc. SPIE 9719, Biophysics, Biology, and Biophotonics: the Crossroads, 971905 (Presented at SPIE BiOS: February 13, 2016; Published: 9 March 2016); https://doi.org/10.1117/12.2212844.
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Study of self-shadowing effect as a simple means to realize nanostructured thin films and layers with special attentions to birefringent obliquely deposited thin films and photo-luminescent porous silicon