Localized surface plasmon resonance has been extensively investigated for biochemical sensor applications. In traditional localized surface plasmon resonance biosensors, resonance spectra were measured in the reflection or transmission from the nanostructure devices. In this work, we demonstrate a new surface plasmon resonance sensor platform with which the localized surface plasmon resonance and shift were measured by using a CCD imager instead of using an optical spectrometer. In additional to the metal nanostructures which support localized plasmon resonance, we pattern the nanostructures into diffraction gratings with super-wavelength grating periods. The nanostructure diffraction gratings support localized plasmon resonance and also diffract localized plasmon resonance radiations into non-zeroth order diffractions. Plasmon resonance spectrum and shift are measured with a CCD imager in one of the diffraction orders. The new plasmon resonance spectrometer sensor combines the functions of sensing and spectral analysis into one apparatus and is capable of real-time visualization of the biochemical bonding process with an imager.
Hong Guo, Xueli Tian, and Junpeng Guo, "Spectrometer sensor using patterned nano-structure plasmon resonance grating
(Conference Presentation)," Proc. SPIE 9721, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII, 972108 (Presented at SPIE BiOS: February 17, 2016; Published: 27 April 2016); https://doi.org/10.1117/12.2219262.4848770151001.
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