Heavy metal ions released into the environment from industrial processes lead to various health hazards. We propose an on-chip label-free detection approach that allows high-sensitivity and high-throughput detection of heavy metals. The sensing device consists of 2-dimensional photonic crystal microcavities that are combined by multimode interferometer to form a sensor array. We experimentally demonstrate the detection of cadmium-chelate conjugate with concentration as low as 5 parts-per-billion (ppb).
Hai Yan, Naimei Tang, Grace A. Jairo, Swapnajit Chakravarty, Diane A. Blake, and Ray T. Chen, "High-sensitivity high-throughput chip based biosensor array for multiplexed detection of heavy metals," Proc. SPIE 9725, Frontiers in Biological Detection: From Nanosensors to Systems VIII, 972507 (Presented at SPIE BiOS: February 15, 2016; Published: 22 April 2016); https://doi.org/10.1117/12.2212731.
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